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Myasthenia Gravis

Myasthenia Gravis (MG) is an autoimmune disease of the neuromuscular junction in which antibodies target the acetylcholine receptor at the muscle-endplate. We are investigating the pathogenesis of a complication of Myasthenia Gravis affecting a subset of young subjects of African or recent-African ancestry, who develop a severe and treatment-resistant form of external ophthalmoplegia, which is accompanied by significant morbidity and functional visual impairment.

The Myasthenia Gravis Group is part of the Neurosciences Research Group; a collaboration between the Department of Medicine and the Department of Cell Biology at the University of Cape Town.

The Myasthenia Gravis group is led by Professor Jeanine Heckmann and group members include Drs Robea Ballo, Melissa Nel and Robyn Rautenbach.